Autosomal Dominant Polycystic Kidney Disease: Mutation Database PKD logo
Acknowledgements Main Page

This database was designed and developed by the following key individuals:
Version 1:
Alex Gout
Data collation, curation and database construction. 		Neilson Martin
Hardware set-up, software configuration and programming. 		David Ravine
Data collation and resource conceptualization.

Version 2.1:
Brian Wilson
Database Design & Programming. 		Sandro Rossetti
Database Curation 		Peter Harris
Database Curation.


It would not have been possible without guidance, critical comments and assistance from the following:
Martijn Breuning, Leiden, The Netherlands
David Cooper, Cardiff, UK
Lisa Guay-Woodford, Birmingham, USA
Heikki Lehvaslaiho, Hinxton, Cambridge, UK
Teri Watnick, Baltimore, USA
 Alastair Brown, Edinburgh, UK
Dick Cotton, Melbourne, Australia
Dorien Peters, The Netherlands
Vicente Torres, Rochester, USA
 Arlene Chapman, Atlanta, USA
Greg Germino, Baltimore, USA
Michael Krawczak, Kiel, Germany

Their professional expertise and willing help when needed is gratefully acknowledged.
Financial support for this database has been provided by the PKD Foundation.
References
SIFT

Ng PC, Henikoff S.
Predicting Deleterious Amino Acid Substitutions,
Genome Res. 2001 May; 11(5): 863.874.

Ng PC, Henikoff S.
Accounting for Human Polymorphisms Predicted to Affect Protein Function,
Genome Res. 2002 December; 436-446

Ng PC, Henikoff S.
SIFT: predicting amino acid changes that affect protein function,
Nucleic Acids Research, 2003, Vol. 31, No. 13 3812-3814

 Align GVGD

Tavtigian SV, Deffenbaugh AM, Yin L, Judkins T, Scholl T, Samollow PB, de Silva D, Zharkikh A, Thomas A.
"Comprehensive statistical study of 452 BRCA1 missense substitutions with classification of eight recurrent substitutions as neutral."
J Med Genet. 2005 Jul 13; [Epub ahead of print]

Mathe E, Olivier M, Kato S, Ishioka C, Hainaut P, Tavtigian SV.
"Computational approaches for predicting the biological effect of p53 missense mutations: a comparison of three sequence analysis based methods."
Nucleic Acids Res. 2006 Mar 6;34(5):1317-25. Print 2006.
PMID: 16522644 [PubMed - indexed for MEDLINE]